Brainlab and Precision NeuroMed Launch AI-Enabled CED Treatment Planning Platform
Context and Chronology
Two specialist firms have formed a product-level alliance to industrialize intracerebral drug delivery planning. Brainlab brings imaging integration and operating-room software; Precision NeuroMed contributes molecular flow simulation and clinical drug programs. The joint work targets a cloud-hosted treatment planning system for convection enhanced delivery (CED) meant to raise reproducibility across surgical teams. Initial development will prioritize the planning needs for PNM-201, a lead investigational therapy for recurrent glioblastoma.
The engineering objective is to merge volumetric imaging, physics-based distribution models, and optimization routines into a single planning workflow that clinicians can review and iterate. The partners expect the platform to reduce inter-operator variability by codifying catheter placement, infusion parameters, and expected drug spread. Mr. Birkenbach framed the software as a clinician-facing tool to increase planning confidence in complex neuro-oncology cases. Dr. Kunwar described the product as a route to scale targeted brain therapies beyond specialized centers.
Commercial structure includes joint development with equity alignment and shared commercialization rights, signalling more than a vendor integration—this is a strategic product partnership. By combining software distribution channels and clinical programs, the companies can couple platform adoption to ongoing trials and future drug launches. The teams plan a cloud-native architecture so community hospitals and academic centers can access standardized plans without heavy local compute. Links to company pages and the public notice are available at Brainlab and Precision NeuroMed.
If adopted, the planner could broaden indications far beyond glioblastoma, enabling precise delivery pathways for gene therapies, biologics, and payloads for Parkinson’s, epilepsy, and Alzheimer’s programs. Regulatory review will shift from solely assessing a drug to also evaluating a software-mediated delivery method and its validation data. Hospital procurement and trial sponsors will gain a lever to reduce procedural heterogeneity, but vendor lock and data governance will become negotiating points. Expect competing imaging and planning vendors to respond with similar integrated solutions or partnerships that tie software to specific delivery hardware.
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